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Wednesday 24 June 2015

Predicting chronic pain in whiplash injuries ?

Scientists identified who will develop chronic pain 1 to 2 weeks after whiplash injury:
  • Large amount of fat in neck muscles predicts chronic pain, disability and PTSD
  • Will enable earlier treatment for whiplash victims
  • Fat indicates atrophy, shows the chronic pain is not psychological
  • Whiplash affects more than 4 million Americans annually
While most people should expect to fully recover from whiplash injuries within the first few months, about 25 percent have long-term pain and disability that lasts many months or years.

Using special MRI imaging, Northwestern Medicine scientists have identified, within the first one and two weeks of the injury, which patients will go on to develop chronic pain, disability and post- traumatic stress disorder (PTSD). This is the earliest these patients have ever been identified, according to the scientists.

The ability to identify these patients so early will enable faster and more specialized treatment, which could be particularly beneficial for the PTSD.

After one to two weeks of the injury, Northwestern scientists found unusual muscular changes in the chronic pain group using a sophisticated MRI that measures the fat/water ratio in the muscles. The imaging revealed large amounts of fat infiltrating the patients' neck muscles, indicating rapid atrophy.
The presence of fat in the muscle does not appear to be related to a person's body size or shape.

"We believe this represents an injury that is more severe than what might be expected from a typical low-speed car crash," said lead investigator James Elliott, assistant professor of physical therapy and human movement sciences at Northwestern University Feinberg school of Medicine. The study was published in the journal Spine.

"This opens up a new door for research on whiplash," Elliott said. "For a long time whiplash has been treated as a homogenous condition. Our study has shown these patients are not all the same; they have different clinical signs and symptoms."

Whiplash-associated disorders from motor vehicle collisions affect more than 4 million Americans annually, harming their quality of life and costing an estimated $30 billion for medical/rehabilitative care per year.

The study, which used standard MRI imaging, also found a large amount of fat in neck muscles of whiplash patients at one and three months post injury. Those patients went on to develop chronic pain and disability.

Not everyone needs a MRI scan after a whiplash injury from a motor vehicle collision. However, these findings help physicians understand water/fat MRI, in tandem with other clinical signs/symptoms can be used to identify who is likely to develop post-traumatic stress disorder. This then could be used to justify the referral of the patient to a psychiatrist or psychologist, Elliott said. PTSD is a disorder caused by experiencing or witnessing a traumatic event.

The patients have shown to not respond well to traditional rehabilitation such as physical therapy. It appeared that they may require a more concerted effort for pain management from their physician and help from a psychologist. Emerging, yet preliminary evidence suggests this to be a reasonable strategy.
The findings may indicate the importance of changing standard imaging protocols to identify these individuals early and start accelerated treatment. Routine imaging does not reveal this fat infiltration in individuals with whiplash injuries.

A small preliminary study previously done by Elliott and Northwestern colleagues shows whiplash victims with chronic pain also have a high level of muscle fat in their lower legs, indicating muscle atrophy.

Elliott hypothesizes these patients may have partially damaged their spinal cord. They reported feeling fatigued and clumsy when walking and weakness in their legs, with difficulty pushing hard on the gas pedal of a car or standing on their tiptoes.

Effective treatment for these patients with chronic whiplash is not yet available. This is mainly due to the fact that it has nt been figured out what's wrong with them.

The findings help to demystify the condition and let individuals know their chronic pain is not all in their heads. A basic exam will not consistently show a fracture, herniated disc or ligament tear.
Whiplash patients with ongoing chronic pain, but no objective imaging, are frequently informed that nothing is wrong with them, the author concluded. However, it appears to be a response to the injury. But what has actually been injured remains to be found out.




Read more: Northwestern University. (2015, April 6). "Predicting chronic pain in whiplash injuries ." Medical News Today. Retrieved from

Keywords: "Dr Pietsch", "The-Expert-witness.de", "Neck pain",  Whiplash", "Chronic whiplash"

Thursday 11 June 2015

Pre-operative absence from work is a predictor for the return to work after arthroplasty

For patients who undergo total hip or total knee arthroplasty, the most significant predictor of incomplete or no return to work is preoperative absence from employment, new research shows. Preoperative absence from work is a potentially modifiable factor and modification could prevent productivity loss.

Of patients undergoing total hip or total knee arthroplasty, 15% to 45% are of working age. Most return to work after surgery, but some experience a reduction in work hours, and 5% to 30% do not return at all.

A study by Lichtenberg identified the determinants of incomplete or no return to work 1 year after surgery. Leichtenberg presented results from the prospective cohort study here at the 16th European Federation of National Associations of Orthopaedics and Traumatology Congress in Prague.

Of the 123 study participants, 67 underwent total hip arthroplasty and 56 underwent total knee arthroplasty. All were younger than 65 years and had a paid job at the time of surgery.
Sociodemographic characteristics were matched in the hip and knee groups using pain, other symptoms, function in daily living, function in sport and recreation, and quality of life subscores of the Hip Disability and Osteoarthritis Outcome Score or the Knee Injury and Osteoarthritis Outcome Score.

Patients were evaluated before surgery and 1 year after surgery. The primary outcome — return to work 1 year after surgery — was classified as complete, incomplete, or not at all.
The researchers categorized the physical demands of each patient's work as light, medium, or heavy. The rate of patients with physical work categorized as light was lower in the hip group than in the knee group (70% vs 87%).

 Work Characteristics and Outcomes
Variable Hip Group, % Knee Group, %
Characteristic
   Self-employed 18 15
   On workers' compensation the month before surgery 8 11
   Need for work adaptations 24 35
   Absence from work due to pain 32 32
Work at 1 year
   Complete 79 71
   Incomplete 13 18
   Not at all 8 11

Preoperative absence from work was the only factor associated with no or incomplete return to work in both the hip group (odds ratio [OR], 8.6; 95% confidence interval [CI], 1.9 - 39.0) and the knee group (OR, 4.2; 95% CI, 1.0 - 17.1).

In the hip group, self-employment was strongly associated with no or incomplete return to work (OR, 7.6; 95% CI, 1.5 - 39.8), as was a higher Hip Disability and Osteoarthritis Outcome Score.

A return-to-work appears completely dependent on the insurance system in the specific country. In Sweden, from a financial income standpoint, it doesn't matter if you go back to work; you would be pretty well off on public support. In the United States, it is not that way. Patients were not asked for the reasons why they stopped working after surgery, which is one of the limitations of the study.

However, despite this, the researchers conclude that the proportion of hip and knee patients not returning to work full time is substantial, and that the only predictor of this is preoperative absence from work, which can be changed. 


Leichtenberg, Malchau: More Could Return to Work After Joint Surgery. 16th European Federation of National Associations of Orthopaedics and Traumatology (EFORT) Congress. Presented May 27, 2015.

Monday 1 June 2015

Posture matters in radiographs of clavicle fractures

Objectives: To determine whether clavicle fracture displacement and shortening are different between upright and supine radiographic examinations.
Picture: Dr Pietsch notfallambulanz.blogspot.com

Design: Combined retrospective and prospective comparative study.
Setting: Level I Trauma Center.

Patients: Forty-six patients (mean age, 49 years; range, 24–89 years) with an acute clavicle fracture were evaluated.

Intervention: Standardized clavicle radiographs were obtained in both supine and upright positions for each patient. Displacement and shortening were measured and compared between the 2 positions.
Main Outcomes Measurements: One resident and 3 traumatologists classified the fractures and measured displacement and shortening. Data were aggregated and compared to ensure reliability with a 2-way mixed intraclass correlation.

Results: Fracture displacement was significantly greater when measured from upright radiographs (15.9 ± 8.9 mm) than from supine radiographs (8.4 ± 6.6 mm, P < 0.001), representing an 89% increase in displacement with upright positioning. Forty-one percent of patients had greater than 100% displacement on upright but not on supine radiographs. Compared with the uninjured side, 3.0 ± 10.7 mm of shortening was noted on upright radiographs and 1.3 ± 9.5 mm of lengthening on supine radiographs (P < 0.001). The intraclass correlation was 0.82 [95% confidence interval (CI), 0.73–0.89] for OTA fracture classification, 0.81 (95% CI, 0.75–0.87) for vertical displacement, and 0.92 (95% CI, 0.88–0.95) for injured clavicle length, demonstrating very high agreement among evaluators.

Conclusions: Increased fracture displacement and shortening was observed on upright compared with supine radiographs. This suggests that upright radiographs may better demonstrate clavicle displacement and predict the position at healing if nonoperative treatment is selected.


Keyword: Clavicle fracture, Dr Pietsch, x-ray clavicle fracture and posture